Clinical

Tara Kersey-Barrett and Dr. Greg Sawyer check settings on CO2 incubators.


Endocrine Factors of Post-Partum Depression
This study is looking for a correlation between multiple hormones that change at the time of birth and possibly correlate with the onset of depression. Answers to questions such as, “Is it possible to predict those at high risk?” and “Can hormone therapy be proposed to mitigate symptoms or avert onset?” are studied.
Sponsor: Pfizer, Inc.
PIs: Marty Beal, Gary Watson
GS: Sarah McCoy


An Examination of HIV/AIDS Knowledge and Attitudes Among Medical Trainees

It is estimated that the number of persons with HIV infection in the United States ranges from 650,000 to 900,000. Given these numbers, future physicians can anticipate being involved in the direct care of patients with HIV infection and/or assisting in identifying care resources for them. However, research indicates that a notable percentage of health care professionals have negative attitudes towards HIV-infected and AIDS patients. This research examines the factors that influence knowledge of AIDS and attitudes towards AIDS and HIV-infected patients among medical trainees during their medical education.
Sponsor: College Seed Grant
PIs: Vivian Stevens, Damon Baker


Area Prevention Resource Centers

The Department of Psychiatry administers three Area Prevention Resource Centers (APRCs). Each APRC serves a defined catchment area from offices within its geographical region. The Tulsa APRC serves north and west Tulsa County; the PaNOK APRC provides services to Payne, Pawnee, Noble, Osage, and Kay Counties; and the Tri-County APRC functions in Creek, Okmulgee, and Okfuskee Counties.
These programs promote the prevention of substance abuse and its related problems of domestic violence, child abuse and neglect, youth depression and suicide, teenage pregnancy, STFDs and AIDS, violence, gangs and occult involvement, and school dropouts through services that positively influence the personal attributes of individuals and the environmental conditions of the community. APRCs organize individuals into task forces that assess the mental health needs within their community and, with the assistance of APRC staff members, develop and implement programming to reduce the incidence of high-risk behaviors. APRC community-based programs provide information and education, increase community awareness and citizen involvement, present life skills development training, organize alternative activities, examine social policy, and refer individuals for intervention services as needed.
Sponsor: Oklahoma Department of Mental Health and Substance Abuse Services
PI: Bruce A. Singer


African-American Specialty Center

The goal of the Center is the development of healthy, responsible, productive citizens who will be unlikely to experience alcohol or drug-related problems in their lives. This is accomplished through the delivery of culturally-specific prevention services that identify individual and environmental factors that place African Americans at increased risk and address these conditions.
Sponsor: Oklahoma Department of Mental Health and Substance Abuse Services
PI: Bruce A. Singer


Cognitive Impairment Among Cherokee Elders
A pilot project is being conducted in collaboration with Ralph Richter of St. John Medical Center and the Alzheimer’s Disease Center of the University of Texas Southwestern Medical Center at Dallas dealing with cognitive impairment among Cherokee elders in Oklahoma. The purpose of the study is to obtain preliminary data on the prevalence of cognitive impairment, profiles of cognitively impaired and non-impaired Cherokee elders, and the usefulness of several standard mental health and functional assessment instruments for this population.
Sponsor: College Seed Grant
PI: Nancy Van Winkle


Cognitive Rehabilitation Following Brain Injury

Injury of brain tissue occurs in many diseases and traumatic incidents. Impaired cognitive and perceptual abilities secondary to these injuries often prevent patients from returning to productive work and family life. Rehabilitation therapies have been widely available for only the past twenty years; research into their effectiveness is in its infancy. Current investigation involves examining the efficacy, clinical utility, and cost effectiveness of an in-home computerized cognitive and perceptual rehabilitation system. This research involves collaboration among faculty from OSU-COM and NSU College of Optometry.
Sponsor: College Seed Grant
PI: Richard H. Bost


Contribution of Osteopathic Cranial Manipulation to the Management of Recurrent Otitis Media
The purpose of this research is to establish the value of osteopathic manipulative treatment in the management of children with recurrent otitis media. Ninety percent of all children under three years of age have at least one episode of otitis media (ear infection), and seventy five percent have more than three. Osteopathic physicians find that osteopathic manipulation therapy (OMT) in conjunction with conventional medical treatment will reduce the frequency and severity of recurrent otitis media. These manipulative techniques are not new but have not been well studied in relation to recurrent otitis media. It is believed that the manipulation will improve drainage of the eustachian tube (which normally balances air pressure between the middle ear and the outside air). Drainage of fluid from the middle ear should shorten the length of illness and reduce the discomfort that goes with these illnesses.
Sponsor: AOA
PI: Miriam Mills


End of Life Issues in American Indian Communities
Funding is being pursued to conduct a pilot study in two American Indian tribes to investigate end-of-life issues in these populations. This study will (1) identify the values, beliefs, and behaviors of tribal members regarding end-of-life issues, (e.g., advance directives, autopsies, organ donations), (2) determine tribal members’ and health providers’ perspectives of how the health care system currently deals with these issues, and (3) determine tribal members’ and health providers’ perspectives of how the health care system can be improved to better meet the needs of tribal people regarding end-of-life issues. This is the first step in a research program whose ultimate goal is to develop curricular materials on end-of-life issues to train culturally competent health care providers. This is a collaborative effort with Dianne Miller-Hardy of OSU-COM and Everett Rhoades of OU Health Sciences Center.
Sponsor: College Seed Grant
PI: Nancy Van Winkle


Collaborator: Everett Rhoades, OU Health Sciences Center Oklahoma Area Health Education Center Program

The Oklahoma Area Health Education Center Program (OkAHEC) is a sponsored program of OSU-COM that is conducted through regional AHECs located in Enid, Poteau, Lawton, and Pryor, and a training/health care facility in the Osage Hills Complex in Tulsa. The program combines academic and community resources to improve the supply and distribution of primary care professionals and to increase the accessibility of quality health care services in rural and medically underserved areas. The OkAHEC mission is accomplished through community-based training for health professional students and medical residents with rural and underserved populations; educational interventions that promote disease prevention and improved health through access to primary health care services; continuing education for health practitioners in rural communities; health careers recruitment with a special focus on minority and underserved populations; locally based initiatives that respond to emerging health care needs; and coordination with other state and federal primary care initiatives.
Sponsor: Oklahoma Department of Health, U.S. Department of Health and Human Services
PI: Larry Cherry


Prevention Resource and Evaluation Center
The Prevention Resource and Evaluation Center (PREC) provides consultation, material resource support, and a wide range of program evaluation services for the Oklahoma Department of Mental Health and Substance Abuse Services (DMHSAS), the Oklahoma Area Health Education Centers (OKAHEC), and other agencies throughout the state. Originally developed exclusively for drug and alcohol prevention programs, PREC has expanded its scope to include the evaluation of other health-related topics and provides services, i.e., evaluation design, instrument development, and the production of formal evaluation reports, to many other agencies. The collection, input, analysis, and services offered by PREC staff are survey development and implementation, evaluation site visits, conducting informational or training presentations on evaluation or related topics, and providing consultation or technical assistance.
Sponsor: Oklahoma Department of Mental Health and Substance Abuse Services
PI: Bruce A. Singer


Stress and Human Motor Activity
Restlessness and psychomotor agitation, i.e., excessive nonproductive or nongoal-oriented motor activity, are symptoms of anxiety. This research examines the use of a body-borne, motor activity measurement device to detect changes in motor activity associated with anxiety-provoking life events. This research may help improve diagnosis and treatment of anxiety disorders by aiding in the development of quantitative methods for reliable, unobtrusive assessment of nonproductive motor activity during daily life and in response to stressful life events.
Sponsor: Department of Psychiatry and Behavioral Sciences
PI: Michael H. Pollak


Suicide Among American Indians in New Mexico
A current outcomes study is being conducted with the Jicarilla Apache Tribe to evaluate the efficacy of their National Model Adolescent Suicide Prevention Project. This study compares the pre- and post-intervention suicide rates of the Jicarilla Apache Tribe and other Apache, Navajo, and Pueblo tribes in New Mexico. Additional studies are being conducted with Philip May of the University of New Mexico to update epidemiological information regarding completed suicides among the Apache, Navajo, and Pueblo Indians in New Mexico from 1957-1998. Quantitative and qualitative data is being reviewed from state death certificates and death reports from the Office of Medical Investigator to develop a more complete epidemiological description of suicide completions. The association of alcohol and suicide, age and gender differences, interactions prior to the event, and trends in suicide rates are all currently being explored in these populations.
Sponsor: Indian Health Service
PI: Nancy Van Winkle


Clinical Drug Trials
Several faculty contract with different pharmaceutical companies to test new drugs. Ongoing trials are testing drugs for the treatment of HIV/AIDS, cardiovascular disease, asthma, and other diseases.